Penn's DB's had no response for the Irish WR's #17, #3 and #8 for Cathedral. #17 at one point seemed to be the only WR that the Irish wanted to throw to and everyone in the stadium knew it (except for the Penn coaching staff). From what I saw, there weren't any adjustments made to slow the passing game down. DB's were giving 8–10 yard cushions for the Irish WR's the entire night. Absolutely no press with over-the-top help and that cost Penn. The Irish QB (Danny O'Neil) has a good arm and is mobile (I believe his dad played at Penn years back) and showed why he is going to Colorado.
Penn's QB had a decent game but didn't seem too comfortable in the pocket. It looks like he injured his right ankle which definitely hindered his ability to rollout and pass. There were some drops and overthrows to the receivers too. After a muffed snap on a punt, Penn got the ball at the Cathedral 17 or so yard line and got to the 4 yard line before being stopped on 4th down.
On a positive note, Penn did hold down the Irish rushing game. Most of their rushing yards came in the 3rd/4th quarters when there was a running clock.
The thing that jumped out at me the most was that Penn seemed like they wanted to be anywhere but that field. Coming onto the field at the very beginning there was no intensity or emotions. It was like they were zombie walking. Cathedral punched them in the mouth, and they never recovered.
These were just my observations of the game.