The landscape of football now is different than what it was in the 90's. A good team could obliterate a weak schedule and still win the 5A (now 6A) championship. To make a run to Lucas and expect to win, you have to see at least one, preferably two title contending teams. I think Penn should pick up one team from Fort Wayne (Carroll or Snider) and one team from Indy (pick from ten).
Penn and Center Grove could be on equal footing, but if Penn doesn't see the caliber of a Top 10 team during the regular season, it will be like hitting a brick wall when they do. For Center Grove, it's just another day at the office, it's nothing new to them to play a team like Penn. I'll take the Trojans by two touchdowns in that scenario.
Scheduling Mishawaka is fine if you're shooting for the 5A title. But 6A is another ball game.